Table 1.
Description of the ligands and functions of the surface markers studied
Surface marker | Designation | Ligand(s) | Function |
CD11a | CD54, CD102 | Adhesion, T cell development | |
CD33 | Sialylated glycoproteins? | Functions in haematopoesis | |
CD45RA | Signal transduction | ||
CD45RB | Signal transduction | ||
CD45RO | Signal transduction | ||
CD49d | α4-integrin | VCAM-1, fibronectin, MAdCAM-1, invasin | Adhesion, embryonic development |
CD54 | ICAM-1 | LFA-1 (CD11a/CD18), Mac-1 (CD11b/CD18), CD43 | Adhesion, leucocyte transendothelial migration, signal transduction |
CD62L | L-selectin | DNAd (CD34, GlyCAM-1, MAdCAM-1) | Adhesion; leucocyte homing, rolling and extravasation |
CD86 | B 7-2 | CD28, CD152 | T cell interaction with dendritic cells and B cells, B cell co-stimulation |