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Leprosy patients with reaction show enhanced spontaneous apoptosis ex vivo. Evaluation of spontaneous apoptosis was assayed in PBMC (solid bars) cultures and CD14+ cells (hatched bars) obtained from leprosy patients with (n = 4) or without (n = 6) reaction (ENL). The rate of apoptosis was evaluated through 7-AAD staining and percentage of apoptotic cells was determined by flow cytometry analysis. *Significant differences when compared to unreactional patients.
