Figure 2.

λ-Carrageenan induced inflammation, representative of neutrophil-mediated inflammation. Micrometer-measured increases in footpad swelling in mice injected with λ-carrageenan intradermally into the footpad, and treated with PBS; UTβ4 or its methionated derivative; LTβ4 or its methionated derivative. (a) At 24 hr, mice that received LTβ4 had a significantly reduced footpad swelling than mice receiving either PBS or UTβ4. (b) At both 6 hr and 24 hr mice that received mlTβ4 had a significantly reduced footpad swelling than mice receiving either PBS or mUTβ4.