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. 2003 Jul;109(3):351–359. doi: 10.1046/j.1365-2567.2003.01671.x

Figure 3.

Figure 3

Downregulation of LAT expression after cross-linking of the precursor B-cell receptor (pre-BCR) with Igβ. (a) 1xN/2b cells were incubated in vitro with different concentrations of anti-Igβ antibody for 72 hr: (1) background staining for LAT with normal rabbit serum; (2) with normal hamster immunoglobulin G (IgG) (10 µg/ml); (3) with anti-Igβ antibody (1 µg/ml); or (4) with anti-Igβ antibody (10 µg/ml). Cells were analysed as described in the legend to Fig. 2. Results are representative of three different experiments. (b) Bone marrow cells from µMT/µMT mouse were incubated with normal hamster IgG (2) or with 10 µg/ml of anti-Igβ antibody (3) for 72 hr. (1) background staining for LAT with normal rabbit serum. Cells were analysed as described in the legend to Fig. 2. Results are representative of three different experiments.