Figure 6.
Proliferative responses [in counts per minute (c.p.m.)] upon stimulation with anti-immunoglobulin M (anti-IgM) antibody or lipopolysaccharide (LPS). Spleen B cells from wild-type (WT) or LAT transgenic (Tg) mice were stimulated with goat F(ab′)2 anti-IgM antibody (5 or 10 µg/ml) or LPS (5 µg/ml). Cells were cultured for 48 hr and pulsed with [3H]thymidine. All assays were performed in triplicate. Bars show the standard deviation (SD). The experiments were repeated twice and gave similar results on each occasion.