Table 1.
Constructs # | Mutated motifs | Wild-type sequences | Mutation sequences |
---|---|---|---|
″9 | AP-1 motif at −3471 | aaataagagagattgagtgacagcttgaagggg | aaataagagagattgCAtgacagcttgaagggg |
10 | PEA-3 motif at −3836 | gggagtctgaggcaggaagattgcttaagccca | gggagtctgaggcagTCagattgcttaagccca |
11 | CREB motif at −3187 | ggtaaccatgaggactgacggaaccagtgtgtacc | ggtaaccatgaggactTaTggaaccagtgtgtac |
12 | AP-1 motif at −72 | atgttataaagcatgagtcagacacctctggct | atgttataaagcatgCAtcagacacctctggct |
13 | PEA-3 motif at −88 | atagctaatcaagaggatgttataaagcatgag | atagctaatcaagagTCtgttataaagcatgag |
The motifs are underlined. The mutated nucleotides are indicated by capital letters.