Table 3.
Frequency of Chlamydia-specific proliferative T-cells and antibody secreting B-cells in three strains of mice the day before the genital challenge
| Mouse strain | Frequency of Chlamydia-specific proliferative T- cells (±1SD)/106 | Frequency of Chlamydia-specific antibody secreting B-cells (± 1SD)/106 splenocytes† | ||
|---|---|---|---|---|
| Group | Splenocytes* | IgG | IgA | |
| C3H/HeN | Immunized | 30 ± 0·6 | 35 ± 14 | 170 ± 28 |
| Sham immunized | 2 ± 0·08 | 0 ± 0 | 2 ± 3 | |
| C57BL/6 | Immunized | 33 ± 0·6 | 160 ± 63 | 173 ± 10 |
| Sham immunized | 4 ± 0·09 | 0 ± 0 | 2 ± 3 | |
| BALB/c | Immunized | 28 ± 0·5 | 95 ± 0 | 208 ± 3 |
| Sham immunized | 6 ± 0·14 | 2 ± 3 | 5 ± 0 | |
*
Precursor frequency of Chlamydia-specific proliferative T-cells was measured by limiting dilution analysis.
†
Frequency of Chlamydia-specific antibody secreting B-cells was enumerated by an ELISPOT assay.