Table 6.
Fertility studies of three strains of mice
| Mouse strain | Group | No. mice with bilateral fertility/total mice (%) | Mean ± 1 SD no. embryos per mouse per uterine horn | |
|---|---|---|---|---|
| Right* | Left† | |||
| C3H/HeN | Immunized, challenged | 17/17 (100) | 3·5 ± 2·0 | 2·9 ± 1·5 |
| Sham immunized, challenged | 0/14 (0)‡ | 0·9 ± 2·4§ | 0·1 ± 0·3§ | |
| Sham immunized, non-challenged | 17/19 (89·5) | 3·2 ± 1·9 | 3·4 ± 1·1 | |
| C57BL/6 | Immunized, challenged | 15/18 (83·3) | 3·7 ± 2·4 | 3·2 ± 2·3 |
| Sham immunized, challenged | 3/18 (16·7)‡ | 2·4 ± 3·0 | 0·2 ± 0·4§ | |
| Sham immunized, non-challenged | 9/11 (81·8) | 3·8 ± 2·6 | 3·8 ± 1·9 | |
| BALB/c | Immunized, challenged | 16/16 (100) | 4·4 ± 2·0 | 3·4 ± 1·5 |
| Sham immunized, challenged | 3/20 (15)‡ | 3·1 ± 3·1 | 0·6 ± 0·6§ | |
| Sham immunized, non-challenged | 20/21 (95·2) | 4·1 ± 2·0 | 3·0 ± 1·7 | |
*
Inoculated with HeLa cell extracts.
†
Inoculated with 105 IFU of C. trachomatis MoPn.
‡
P < 0·05 by Fisher's exact test compared to the sham immunized, non-challenged mice.
§
P < 0·05 by Student's t-test compared to the sham immunized, non-challenged mice.