Figure 6.

Effects of several eicosanoids (a) and dose–response effects of carbocyclic-thromboxane-A₂ (ccTXA₂) (b) on cytokine levels. After a 2-day culture period, cells were exposed to the eicosanoids (1 µm) outlined and stimulated (at the same time) with lipopolysaccharide (LPS). Cytokine levels were measured in the supernatants 20 hr after the induction of LPS stimulation. Data represent mean ± standard error of the mean (SEM). (a), n = 8; (b), n = 3. Control incubations were conducted in the absence of eicosanoids.