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C5a has no effect of surface molecule expression of DC. Immature DC, DC(PGE2) and DC(IFN-γ) stimulated with C5a did not change the expression of surface molecules as shown here in one representative experiment (out of 11) for HLA-DR and CD86. Note that mature DC(PGE2) have a considerable increase in HLA-DR and CD86 expression as compared to the unstimulated controls.
