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Expression of MCP-1 and IFN-γ message in the lungs of M. tuberculosis-infected mice. Lung lobes were collected from individual mice at several time-points throughout the study. Total RNA was isolated, transcribed, and probed using primers specific for HPRT, MCP-1 and IFN-γ. Messenger RNA from the lungs of three individual wild-type mice (a), or three individual mice which had received pentoxifylline (b), are shown at either 150 or 220 days postinfection.
