Figure 6.
Addition of transforming growth factor-β1 (TGF-β1) induces Langerhans'-type cell derivation. Electron micrographs are presented of monocyte-derived Langerhans' cells (MoLCs) showing (a) dendrite details (magnification × 10500) and (b) a Birbeck granule (magnification × 92000). (c) Proliferative responses of 2 × 105 porcine peripheral blood mononuclear cells (PBMC) to allogeneic mitomycin-treated monocyte-derived dendritic cells (MoDCs) (open histogram) or MoLCs (solid histogram) after 5 days of culture. Data shown are representative of three experiments. IP, index of proliferation (see Materials and methods).