Table 1.
Fertility of animals used in this study
| B6 females | B6-4KO females | |||
|---|---|---|---|---|
| Unprimed | Primed | Unprimed | Primed | |
| Mice mated | 18 | 26 | 29 | 32 |
| Matings | 36 | 52 | 58 | 64 |
| Pregnant | 11 | 17 | 12 | 17 |
| No. of litters* | 15 | 23 | 17 | 26 |
| Litters included in analysis | 12 | 15 | 16 | 21 |
Primed mice received an intraperitoneal injection of B6-4KO male spleen cells followed by either placement of a B6-4KO male skin graft or a repeat injection of male spleen cells.
There was no significant difference in the fertility in any group of mice as measured by the number of litters/mouse-matings.
*
Litters not included in the analysis were either eaten by their unprimed (3 B6 and 1 B6-4KO) or primed (6 B6 and 1 B6-4KO) mothers or were born to primed mothers whose anti H-Y CTL activity could not be assessed.