Figure 2.

Effect of ZB4 anti-Fas antibody on PBL apoptosis in untreated coeliac disease. Antagonistic ZB4 reduces Fas-dependent PBL apoptosis. PBL from active coeliac disease and healthy volunteers were incubated for 24 hr in the absence (open bars) or presence (black bars) of 2 µg/ml ZB4 antagonistic antibody. The percentages of apoptotic cells were determined by PI staining by flow cytometry. Results are expressed as the means±SD of three independent experiments.