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Changes in the lymphocyte populations of antibody-treated SOCS1−/− mice compared to age-matched antibody-treated SOCS1+/+ mice. (a) Increased proportion of B220+ IgM+ cells in the lymph node of weanlings. (b) Loss of CD4+ CD8+ T cells in the thymus of adults and increased percentage of CD8+ T cells. Increased expression of the activation marker CD44 on thymocytes.
