Table 2.

T-cell numbers in the bone marrow and spleen of IL-2^−/− mice^*

		Source of cells
Cell subpopulation	Age (weeks)	IL-2−/−	IL-2+/+
Bone marrow
CD4+	8–10†	3·9 ± 1·7‡	0·7 ± 0·5
	11–13	7·7 ± 5·0	0·9 ± 0·1
	22–26	3·2 ± 0·9	0·8 ± 0·1
CD8+	8–10	9·9 ± 3·7‡	1·0 ± 0·0
	11–13	7·0 ± 1·8	1·2 ± 0·5
	22–26	3·5 ± 1·2	0·9 ± 0·3
Spleen
CD4+	8–10	32·0 ± 18·5	9·6 ± 4·0
	11–13	21·6 ± 11·1	10·5 ± 8·2
CD8+	8–10	57·2 ± 34·5	11·9 ± 3·8
	11–13	27·1 ± 16·9	13·4 ± 8·7

^*Bone marrow and spleen cells were collected from IL-2^−/− and IL-2^+/+ mice between the ages of 8 and 26 weeks. Cell subpopulations were identified by flow cytometry.

^†The numbers of mice per group and the total cell numbers are given in Table 1.

^‡Values represent the mean ± SD of the number of cells (×10⁶) in each subpopulation determined by multiplying the % of bone marrow or spleen CD4⁺ or CD8⁺ cells by the total number of cells obtained from bone marrow (femurs) or spleen of each animal. Bone marrow and spleen gates include lymphocytes only.