Figure 1.

Production of interleukin-12 (IL-12) by spleen cell cultures, and corresponding blood parasite counts, after intraperitoneal (i.p.) infection of C57Bl/6 mice with 5000 Trypanosoma cruzi blood forms. The cultures were stimulated with parasite antigen (T-Ag) or incubated in culture medium alone. Values are expressed as arithmetic means from duplicate cultures ±standard deviation (for IL-12) or from six mice (parasite counts). The results are representative of four experiments.