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. 2001 Dec;104(4):439–446. doi: 10.1046/j.1365-2567.2001.01332.x

Figure 3.

Figure 3

Effect of tumour necrosis factor-α (TNF-α) neutralization on the macrophage (Mφ) nitrite response to lipopolysaccharide (LPS). Murine peritoneal Mφs were cultured in medium alone, or with LPS (10 µg/ml) in the presence or absence of the neutralizing anti-TNF-α antibody TN3.19.12. After 48 hr, culture supernatants were harvested and nitrite levels determined by the Griess reaction. Results are expressed as mean±SEM and are representative of two similar experiments. *P < 0·01, TN3.19.12 treatment compared to the LPS-alone control.