Table 1.
Growth of HNSCC tumors in mice injected with CD44+Lin− or CD44−Lin− cells
| Sample (% CD44+) | Population | Cell count, in thousands |
|||||||
|---|---|---|---|---|---|---|---|---|---|
| 500–650 | 200–300 | 100–150 | 40–50 | 20–25 | 10 | 5 | 2 | ||
| UMHN1* (13.4) | CD44+ | 1 of 1 | |||||||
| CD44− | 0 of 1 | ||||||||
| UMHN2* (16.4) | CD44+ | 2 of 2 | 1 of 2 | 1 of 1 | |||||
| CD44− | 0 of 2 | 0 of 1 | |||||||
| UMHN3† (12.0) | CD44+ | 1 of 1 | 3 of 3 | ||||||
| CD44− | 0 of 3 | 0 of 3 | 0 of 3 | ||||||
| UMHN4* (10.4) | CD44+ | 1 of 1 | |||||||
| CD44− | 0 of 1 | 0 of 1 | 0 of 1 | 0 of 1 | |||||
| UMHN5† (0.43) | CD44+ | 1 of 1 | 1 of 1 | 1 of 2 | |||||
| CD44− | 0 of 1 | 0 of 2 | |||||||
| UMHN6** (1.7) | CD44+ | 1 of 1 | 0 of 1 | ||||||
| CD44− | 0 of 2 | ||||||||
| UMHN7† (5.2) | CD44+ | 1 of 1 | 0 of 1 | ||||||
| CD44− | 0 of 1 | ||||||||
| SUHN1* (35.1) | CD44+ | 3 of 3 | 1 of 2 | 0 of 1 | 0 of 4 | 0 of 1 | |||
| CD44− | 1 of 6 | 0 of 2 | 0 of 2 | 0 of 2 | 0 of 1 | ||||
| SUHN2* (1.3) | CD44+ | 1 of 1 | |||||||
| CD44− | 0 of 1 | 0 of 2 | 0 of 1 | ||||||
UMHN samples were all grown in NOD/SCID mice. SUHN samples were all grown in RagγDKO mice.
*Samples that were passaged once through mice before sorting for CD44+ and CD44− populations.
†Samples that were directly sorted from patient samples for CD44+ and CD44− populations.