Figure 2.
Deletion of CaV1.3 disrupts normal consolidation, but not acquisition, of contextual fear conditioning. (A) CaV1.3 knockout mice and wild-type littermates exhibit similar levels of freezing 1 h following a trial of contextual fear conditioning. (B) CaV1.3 knockout mice and wild-type littermates exhibit similar levels of freezing 6 h following a trial of contextual fear conditioning. (C) CaV1.3 knockout mice exhibit significantly less freezing when compared with their wild-type littermates 24 h after a conditioning trial. *P < 0.05 for post hoc comparison between genotypes. All data are presented as mean ±SEM.