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. 2007 Jan 17;7:1. doi: 10.1186/1472-6882-7-1

Table 1.

General scheme of the study

Phase A Phase B
Randomisation
 by cages graphic file with name 1472-6882-7-1-i1.gif graphic file with name 1472-6882-7-1-i1.gif
 within cages by treatments - graphic file with name 1472-6882-7-1-i1.gif
Blinding
 Treatment administration - graphic file with name 1472-6882-7-1-i1.gif
 Edema measurement graphic file with name 1472-6882-7-1-i1.gif graphic file with name 1472-6882-7-1-i1.gif
Inflammation model CA BL CA
Homeopathic remedies
dilution n. of animals studied
 Arnica D4 71 O/I O/I -
 Apis D4 90 O/I O/I O
 Apis D30 18 - - O
 Atropa D4 72 O/I O/I -
 Hamamelis D4 72 O/I O/I -
 Lachesis D6 86 O/I O/I O
 Lachesis D30 18 - - O
 Phosphorus D6 90 O/I O/I O
 Phosphorus D30 18 - - O
Reference treatments
 Placebo:
  Physiological solution 86 O/I O/I O
 Active comparator:
  Indomethacin 88 I/I I/I I

O = oral administration

I = administration through injection

CA = carrageenan induced edema

BL = autologous blood induced edema

Each treatment group has been tested through 3 replications. In each replication 6 rats were studied. In experiment A 11 rats were excluded from the analyses because of problems with edema induction.