Table 3.

Experiment A: Carrageenan edema and administration by sub plantar injection

Drug	Paw volume increase over time (ml ± SD) and effect (% of negative control)
	1 hr		3 hr		5 hr		7 hr
Saline	0.63 ± 0.09		0.92 ± 0.14		0.84 ± 0.13		0.81 ± 0.14
Arnica D4	0.59 ± 0.15	-7	0.90 ± 0.14	-2	0.86 ± 0.15	3	0.74 ± 0.15	-8
Apis D4	0.57 ± 0.08	-10	0.83 ± 0.14	-10	0.80 ± 0.13	-5	0.67 ± 0.12	-17
Atropa D4	0.61 ± 0.09	-4	0.96 ± 0.09	4	0.81 ± 0.10	-3	0.74 ± 0.15	-9
Hamamelis D4	0.62 ± 0.13	-3	0.95 ± 0.15	3	0.87 ± 0.17	5	0.69 ± 0.12	-15
Lachesis D6	0.64 ± 0.16	1	0.86 ± 0.22	-7	0.85 ± 0.20	2	0.81 ± 0.12	0
Phosphorus D6	0.59 ± 0.09	-8	0.94 ± 0.13	2	0.88 ± 0.16	6	0.74 ± 0.13	-9
Indomethacin i.m.	0.54 ± 0.12	-14	0.69 ± 0.12	-25	0.63 ± 0.11	-25	0.49 ± 0.05	-40

ANOVA results. Treatment: F(7,86) = 8.55, p < 0.0001; Time: F(3,258) = 221.19, p < 0.0001; Treatment × time: F(21,258) = 3.18, p < 0.0001.

Bold characters denote significant comparisons (by Student t test) vs. Saline group corresponding for time since edema induction.