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. 2006 Dec;8(12):1037–1041. doi: 10.1593/neo.06634

Table 1.

Radiobiologic Parameters of SiHa Cervical Cancer Cells (mean ± SEM).

Treatment PE (%) D0 (Gy) Dq (Gy) n LD50 (Gy) Dose Enhancement Ratio LD10 (Gy) Dose Enhancement Ratio
Oxic Control 50.6 ± 3.8 1.91 [0.16] 2.46 [1.0] 7.92 2.48 ± 0.48 - 5.26 ± 0.38 -
MG-132 38.1 ± 5.4 0.75 [0.39] 1.51 [3.7] 7.57 1.26 ± 0.25* 1.96 ± 0.54 3.23 ± 0.32* 1.63 ± 0.2
3x Reoxygenation 47.6 ± 4.2 0.9 [0.16] 2.05 [1.1] 11.18 1.63 ± 0.6 1.52 ± 0.64 3.9 ± 0.63 1.35 ± 0.24
3x Reoxygenation MG-132 42.4 ± 6.4 0.7 [0.37] 1.44 [3.5] 7.95 1.16 ± 0.18* 2.14 ± 0.53 3.01 ± 0.24* 1.75 ± 0.19
Hypoxia Control 44.8 ± 2.1 3.41 [0.98] 0.81 [1.9] 1.27 2.97 ± 0.11 - 8.5 ± 0.13 -
MG-132 41.7 ± 3.5 3.05 [1.14] 1.84 [4.9] 1.82 3.62 ± 0.44 0.82 ± 0.10 8.46 ± 0.36 1.00 ± 0.05
3x Reoxygenation 44.3 ± 10 3.63 [1.6] 0.0 [3.7] 1 2.52 ± 0.33 1.17 ± 0.15 8.4 ± 0.46 1.02 ± 0.06
3x Reoxygenation MG-132 33.1 ± 1.8* 2.46 [0.85] 4.29 [1.1] 5.74 5.2 ± 0.16* 0.57 ± 0.03 9.47 ± 0.19* 0.9 ± 0.02
1x Reoxygenation 47.2 ± 1.9 3.27 [1.3] 1.56 [1.9] 1.6 3.64 ± 0.13* 0.86 ± 0.1 8.6 ± 0.20 0.99 ± 0.03
15x Reoxygenation 28.1 ± 1.1* 1.96 [0.42] 1.63 [1.0] 2.3 2.45 ± 0.31 1.12 ± 0.09 6.1 ± 0.23* 1.38 ± 0.06

Ninety-five percent confidence intervals are presented in square brackets.

*

P < .05.