TABLE 2.
Strain genotype | arg8m reversion ratea | Petite frequency (%)a,b | Nuclear mutation rate
|
|
---|---|---|---|---|
YPD | YPG | |||
Wild type | 0.02 × 10−6 (1) | 4.9 (1) | 0.6 × 10−8 | 5.4 × 10−8 |
pos5 | 1.00 × 10−6 (50) | 27 (6) | 0.25 × 10−8 | 6.4 × 10−8 |
pFL39:mip1-exo− | 0.12 × 10−6 (6) | 20 (4) | NDc | ND |
pos5/pFL39:mip1-exo− | ND | 72 (15) | ND | ND |
Reversion rate per cell per generation. Values in parentheses are normalized to the wild-type value.
Petite frequency is the combined frequencies of white versus total (red and white) colonies from three independent experiments done with the YPH925 strain with the pFL39 plasmid present.
ND, not done.