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. Author manuscript; available in PMC: 2007 Jan 29.
Published in final edited form as: Toxicol Appl Pharmacol. 2006 Oct 4;217(3):363–374. doi: 10.1016/j.taap.2006.09.014

Fig. 4. Effect of TCDD treatment on mitochondrial membrane fluidity.

Fig. 4

Mitochondria were prepared from mouse liver 7 days after treatment with corn oil (open bars) or TCDD (closed bars). Mitochondrial membrane fluidity was calculated as the fluorescence polarization anisotropy, determined using the fluorescence probes 1,6-diphenyl-1,3,5-hexatriene (DPH) and 1-(4-trimethylammoniumphenyl)-6-phenyl- 1,3,5-hexatriene p-toluenesulfonate (TMA-DPH), to probe the hydrophobic lipid interior, and the membrane surface, respectively. Data are presented as the mean value ± S.E. (n = 6). A t-test was used to evaluate statistical significance of differences between group sample mean values.

*P<0.05 versus vehicle-treated mice.