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. Author manuscript; available in PMC: 2007 Jan 29.
Published in final edited form as: Nat Rev Immunol. 2006 Apr;6(4):318–328. doi: 10.1038/nri1810

Figure 1. Schematic illustration of connections between the nervous and immune systems.

Figure 1

Signalling between the immune system and the central nervous system (CNS) through systemic routes, the vagus nerve, the hypothalamic–pituitary–adrenal (HPA) axis, the sympathetic nervous system (SNS) and the peripheral nervous system (PNS) are shown. Figure modified with permission from Molecular Psychiatry REF. 140 © (2005) Macmillan Magazines Ltd.