Table 2.
Cell death status over time
Basal (ModHT group/MiHT group) | Reperfusion (ModHT group/MiHT group) | p Value (ModHT group/MiHT group) | |
Non apoptotic non necrotic cells (annexin negative, PI negative) (%) | 73.86 ± 18.49/67.28 ± 16.40 | 51.20 ± 23.88/71.71 ± 11.35 a | 0.002/0.307 |
Early apoptotic cells (annexin positive, PI negative) (%) | 16.45 ± 13.36/20.70 ± 12.21 | 33.21 ± 17.85/17.62 ± 8.06 a | 0.003/0.180 |
Late apoptotic or necrotic cells (annexin positive, PI positive) (%) | 6.97 ± 3.68/10.49 ± 5.92 | 11.45 ± 5.11/8.90 ± 5.36 | 0.009/0.513 |
Fas positive cells (%) | 15.14 ± 17.85/20.03 ± 14.99 | 31.34 ± 22.54/14.30 ± 10.66 | 0.009/0.081 |
CK (IU/L) | 53.1 ± 21.6/60.2 ± 23.7 | 167.1 ± 158.5/153.8 ± 87.9 | 0.045/0.011 |
CK-MB (IU/L) | 29.13 ± 18.20/20.00 ± 3.62 | 42.25 ± 33.80/37.70 ± 12.18 | 0.355/0.001 |
LDH (IU/L) | 363.0 ± 94.2/334.5 ± 61.6 | 385.4 ± 152.7/363.5 ± 80.1 | 0.723/0.240 |
Troponin I (μg/L) | 0.32 ± 0.33/0.22 ± 0.15 | 1.48 ± 1.37/1.45 ± 0.53 | 0.029/< 0.001 |
Lactate (mmol/L) | 1.53 ± 0.88/1.62 ± 0.91 | 3.60 ± 1.32/3.19 ± 1.19 | 0.002/0.005 |
Results are expressed as means ± standard deviations.
a p < 0.05 compared to ModHT group.
CK, creatine kinase; CK-MB, creatine kinase myocardial band; LDH, lactate dehydrogenase; PI, propidium iodide.