Table 4.
Acid-base, oxygenation, and renal function
| 1.5 to 3.0 g·kg-1·day-1* |
3.0 to 1.5 g·kg-1·day-1† |
|||||||
|---|---|---|---|---|---|---|---|---|
| Short Study (n = 7) | Extended Study (n = 5) | Short Study (n = 5) | Extended Study (n = 5) | |||||
| AA load, g·kg−-1·day−1 | 1.5 (19h) | 3.0 (5 h) | 1.5 (24 h) | 3.0 (24 h) | 3.0 (19 h) | 1.5 (5 h) | 3.0 (24 h) | 1.5 (24 h) |
| pH | 7.29±0.05 | 7.29±0.03 | 7.30±0.04 | 7.26±0.02 | 7.30±0.05 | ND | 7.27±0.02 | 7.24±0.04 |
| Bicarbonate, mmol/l | 20.7±1.1 | 20.0±0.5 | 22.0±1.5 | 19.3±1.5 | 20.6±1.0 | ND | 19.2±0.8 | 17.8±1.1 |
| PaO2, mmHg | 81.9 11.9 | 79.5 2.1 | 73.6 3.5 | 75.3 16.0 | 84.2 16.3 | ND | 71.2 25.9 | 57.6 3.9 |
| Serum creatinine, mg/dl | 0.9 0.1 | ND | 0.9 0.1 | 0.8 0.2 | 0.9 0.1 | ND | 0.8 0.1 | 0.8 0.1 |
Data presented are means ± SD.
*
Received 1.5 g·kg-1·day-1 AA infusion initially and then switched to 3.0 g·kg-1·day-1.
†
Received 3.0 g kg1 day1AA infusion initially, then switched to 1.5 g·kg-1·day-1. ND, data not available.
There was no statistical difference between any observed variable by Student’s t-test for paired data.