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. Author manuscript; available in PMC: 2007 Apr 1.

Published in final edited form as: Am J Physiol Endocrinol Metab. 2005 Nov 1;290(4):E622–E630. doi: 10.1152/ajpendo.00274.2005

Table 8.

R_a of leucine N and glutamine

	1.5 to 3.0 g·kg^-1 day^-1				3.0 to 1.5 g·kg^-1 day^-1
	Short study (n = 7)		Extended study (n = 5)		Short study (n = 5)		Extended study (n = 5)
AA load, g·kg^-1 day^-1	1.5 (19 h)	3.0 (5 h)	1.5 (24 h)	3.0 (24 h)	3.0 (19 h)	1.5 (5 h)	3.0 (24 h)	1.5 (24 h)
Leucine N R_a	340.7± 38.0	427.4± 35.4^†	390.7± 84.2	542.6± 170.8^*	467.0± 94.3	383.7± 60.4	505.9± 59.8	404.7± 57.7^†
Total glutamine R_a	449.0± 37.8	423.7± 37.2^†	439.7± 97.9	548.6± 102.6^**	570.2± 105.4	454.0± 82.9^†	541.8± 60.0	463.3± 40.5^*
De novo glutamine synthesis	384.4± 38.0	368.9± 38.2^†	369.7±92.6	483.4±97.5^†	504.7± 100.2	387.8 ±77.4^†	472.9± 53.4	390.0± 40.7^*

Data presented are means SD. Values for Ra and de novo synthesis are μmol·kg^-1 h^-1. N, nitrogen.

^*

P < 0.05;

^**

P < 0.01;

^†

P < 0.001 as compared with different AA load by Student’s t-test for paired data.