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. Author manuscript; available in PMC: 2007 Jan 30.
Published in final edited form as: Am J Physiol Lung Cell Mol Physiol. 2005 Jan 14;288(5):L932–L941. doi: 10.1152/ajplung.00439.2004

Fig. 3.

Fig. 3

Effect of perineural capsaicin treatment (PNCT) of both cervical vagi on ventilatory responses to intravenous injections of capsaicin and 2APB in anesthetized rats. A and B: ventilatory responses to capsaicin (1 μg/kg) and 2APB (3 mg/kg), repectively, before (open circle), and 5 (capsaicin) or 15 (2APB) min after (filled circle) PNCT of both vagi. f, respiratory frequency; V̇E , minute ventilation. The vertical dashed line depicts time of injection. C and D: apneic responses to capsaicin and 2APB, respectively. Control (open bars), before PNCT; PNCT (solid bars), 5 (capsaicin) or 15 (2APB) min after PNCT; recovery (hatched bars), 60 (capsaicin) or 75 (2APB) min after PNCT. For calculation of apneic ratio, see legend of Fig. 1. Dashed line, apneic ratio of 100% level (no apnea). * Significantly different (P < 0.05) from the corresponding control. Data of each group are means ± SE of 6 rats.