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. Author manuscript; available in PMC: 2007 Jan 30.
Published in final edited form as: Am J Physiol Lung Cell Mol Physiol. 2005 Jan 14;288(5):L932–L941. doi: 10.1152/ajplung.00439.2004

Fig. 7.

Fig. 7

Effect of pretreatment with capsazepine on pulmonary C-fiber responses to capsaicin and 2APB in anesthetized and open-chest rats. A: responses to intravenously injections of 2APB (3 mg/kg) before and 2 min after pretreatment with the vehicle of capsazepine. B and C: responses to intravenously injections of 2APB (3 mg/kg) and capsaicin (1 μg/kg), respectively, before and 2 min after pretreatment with capsazepine (0.3 mg/kg/min; 5 min). BL, baseline fiber activity averaged over 20-s; P, peak fiber activity averaged over 2-s; Veh, vehicle; CPZ, capsazepine; imp, impulses. * Significantly different (P < 0.05) from the corresponding baseline response. † Significantly different (P < 0.05) from the corresponding response before treatment with CPZ or vehicle. Data are means ± SE of 16, 17 and 11 in A, B and C, respectively.