Table 1.
Effect of polyamine analogues in the transcriptional activation of the atoC gene and atoDAEB operon in E. coli strain MA255.
| SUBSTANCES | % β-galactosidase activity MA255/(atoC-lacZ) | % β-galactosidase activity MA255/(atoA-lacZ) |
| Control (Putrescine & spermidine/0.3 mM each) | 100% | 100% |
| 1 mM concentration | ||
| SPERMINE ANALOGUES | ||
| 1 | 67 ± 4.86 | 200 ± 10.66 |
| 2 | 142 ± 8.69 | 181 ± 2.09 |
| 3 | 135 ± 4.69 | 177 ± 1.39 |
| 4 | 43 ± 3.11 | 38 ± 2.38 |
| SPERMIDINE ANALOGUES | ||
| 5 | 78 ± 2.56 | 155 ± 9.12 |
| 6 | 179 ± 10.9 | 114 ± 3.66 |
| 7 | 110 ± 8.50 | 208 ± 8.80 |
| PUTRESCINE ANALOGUES | ||
| 8 | 108 ± 10.93 | 59 ± 5.74 |
| 9 | 119 ± 7.34 | 43 ± 8.80 |
| 10 | 124 ± 10.30 | 64 ± 10.66 |
| 11 | 172 ± 6.42 | 45 ± 5.85 |
| DIAMINOPROPANE ANALOGUES | ||
| 12 | 248 ± 8.02 | 69 ± 8.14 |
| 13 | 169 ± 8.66 | 111 ± 10.24 |
| 14 | 452 ± 2.17 | 218 ± 6.77 |
The data are presented as % activity of β-galactosidase for MA255 cells grown in the presence of 0.3 mM putrescine and spermidine and 1 mM of the indicated polyamine analogue. The values represent the means ± SD from two separate experiments.