Table 1.
Patient characteristics by site
Characteristic | Site 1 | Site 2 | P* |
---|---|---|---|
No. | 41 | 23 | |
Rai stage | |||
Low | 2 | 1 | |
Intermediate | 13 | 14 | .049 |
High | 26 | 8 | |
0 | 2 | 1 | |
1 | 4 | 7 | |
2 | 9 | 7 | .019 |
3 | 12 | 5 | |
4 | 14 | 3 | |
Sex | |||
Male | 32 | 17 | .76 |
Female | 9 | 6 | |
Age, y | |||
Younger than 70 | 29 | 17 | |
70 and older | 12 | 6 | .99 |
ECOG PS | |||
0 | 29 | 5 | |
1 | 11 | 13 | .001 |
2 | 1 | 4 | |
3 | 0 | 1 | |
CD38+ B cells | |||
30% or less | 26 | 15 | .99 |
Greater than 30% | 13 | 8 | |
ZAP-70 B cells | |||
20% or less | 20 | 15 | .07 |
Greater than 20% | 15 | 3 | |
VH status | |||
Mutated | 12 | 6 | .99 |
Nonmutated | 29 | 15 | |
FISH | |||
Normal | 6 | 1 | |
+12 | 8 | 3 | |
11q- | 9 | 4 | |
17p- | 0 | 3 | |
6q- | 1 | 0 | |
13q- | 10 | 10 | |
13q - x1 | 7 | 8 | |
13q - x2 | 3 | 2 | |
Other | 2 | 1 | |
No. of genetic defects | |||
0 | 6 | 1 | |
1 | 16 | 14 | .90 |
2+ | 14 | 7 | |
Bone marrow pattern | |||
Diffuse | 12 | 19 | < .001 |
Not diffuse | 29 | 2 |
P values represent where significant differences were seen between the 2 participating sites.