Table 3.
Structure of individual signal ends made at JH and JL loci of the ovary
| Heavy Chain (JH-SEs) |
|---|
| J H -2 |
| AAAAAGCCGAGGTAGGCTATAGCTATTACTGTGGTTATGGTATGGCTCTTATCTTAAACCTAACCACTGTG |
| AAAAAGCCGAGGTAGGCTATAGCTATTACTGTGGTTATGGTATG −27bps |
| −113bps (CTC addition) |
| −113bps (CTG addition) |
| −155bps |
| −159bps |
| −219bps |
| J H -3 |
| GCGTGTTTGCCAATATTAAGGCAAAATGGTTTGTGTTATTGTGCACTGAATTATAAAAAAGGTTTCACTGTG |
| −226bps |
| −227bps |
| Light Chain (J L -SEs) |
| ACTTCTGTTTGTGTCTCTTCACAGACTGAGGAGGTTTTTGTACGACTGAACATATCAAATCTTTCACTGTG |
| ACTTCTGTTTGTGTCTCTTCACAGACTGAGGAGGTTTTTGTACGACTGAACATATCAAATCTTTCA-5bps |
| −79bps |
| −204bps |
| −216bps |
Signal end sequences are aligned to the germline J gene segments (underlined). The extent of nucleotide loss is indicated by the – number. The heptamer of recombination signal sequence is highlighted as bold.