Figure 7.

Expression patterns of common pathway genes in preleukemic early myeloid cells. Two grouping variable category graphs display raw signal intensity values for the common pathway genes, and for several abundantly expressed azurophil granule genes. Myeloid differentiation studies were performed as shown in Figure 1. Two independent pools of wild-type mice and 2 independent pools of mCG-PML-RARα mice were used in the study. Cells were harvested on days 0 and 2 of differentiation, and array-based expression analysis was performed. The data for the common pathway genes are representative of nearly all genes in the APL dysregulome.