Table 1.
Demographic and Other Baseline Characteristics of Patients Included in This Meta-analysis
| Esomeprazole 40 mg (n = 5068) | Esomeprazole 20 mg (n = 1243) | Omeprazole 20 mg (n = 3018) | Lansoprazole 30 mg (n = 2616) | Total (n = 11,945) | ||
|---|---|---|---|---|---|---|
| Sex, n (%) | Men | 2955 (58) | 763 (61) | 1869 (62) | 1501 (57) | 7088 (59) |
| Women | 2113 (42) | 480 (39) | 1149 (38) | 1115 (43) | 4857 (41) | |
| Age, years | Mean (SD) | 46.6 (13) | 45.0 (13) | 46.3 (13) | 47.4 (13) | 46.4 (13) |
| LA grade, n (%) | A | 1811 (36) | 440 (35) | 990 (33) | 916 (35) | 4157 (35) |
| B | 1945 (38) | 480 (39) | 1203 (40) | 1054 (40) | 4682 (39) | |
| C | 1002 (20) | 240 (19) | 606 (20) | 477 (18) | 2325 (19) | |
| D | 310 (6) | 83 (7) | 219 (7) | 169 (6) | 781 (6.5) | |
| GERD duration, n (%) | < 1 year | 332 (7) | 2 (5) | 178 (6) | 204 (8) | 776 (6.5) |
| 1-5 years | 2171 (43) | 576 (46) | 1290 (43) | 1090 (42) | 5127 (43) | |
| > 5 years | 2564 (51) | 605 (49) | 1550 (51) | 1322 (51) | 6041 (50) | |
| Missing | 1 (0.02) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (0.01) | |
| Heartburn severity, n (%) | None | 74 (1) | 26 (2) | 55 (2) | 20 (2) | 175 (1) |
| Mild | 502 (10) | 110 (9) | 333 (11) | 290 (11) | 1235 (10) | |
| Moderate | 2362 (47) | 615 (49) | 1435 (48) | 1209 (46) | 5621 (47) | |
| Severe | 2128 (42) | 492 (40) | 1192 (39) | 1097 (42) | 4909 (41) | |
| Missing | 2 (0.04) | 0 (0.0) | 3 (0.1) | 0 (0.0) | 3 (0.02) |
LA = Los Angeles classification system; GERD = gastroesophageal reflux disease