Table 1.
The Timing and Recurrence Rate of PBC in the Post-Transplant Setting
| Study (Reference) | Proportion of Patients With Recurrent PBC (%) | Median Time to Recurrence (Yrs [Range]) | Mean Time to Recurrence (Yrs) |
|---|---|---|---|
| Liermann Garcia[13] | 68/400(17.0*) | NR | 3.0 |
| AbuElmagd[21]†‡ | 54/513(10.5) | 5.58(range NR) | NR |
| Sanchez[28] | 17/156(10.9) | 4.13(1.1-7.1) | NR |
| Sylvestre[15] | 17/100(17) | 3.10(0.3-7.9) | 3.7 |
| Hubscher[17] | 13/83(16) | 1.08(1.0-4.0) | 1.7 |
| Sebagh[49] | 6/69(8.7) | 8.00(1.00-8.00) | 6.3 |
| Balan[50] | 5/60(8.3) | 3.00(2.0-6.0) | 4.0 |
| Guy[22] | 17/48(35.0) | NR | 3.3 |
| Levitsky[27] | 7/46(15.0) | 6.50(2.25-10) | NR |
| Khettry[23] | 8/43(18.6) | 3.50(0.1-14) | 5.6 |
| Jacob[20]† | (14.0) | 5.10(3-10.2) | NR |
*
After following this cohort for 10 years, Neuberger reports that this rate has increased to 30%
†
Published in abstract form
‡
Kaplan-Meier analysis shows the estimated cumulative risk of recurrent PBC is 7.9% at 5 years and 21.6% at 10 years
NR = not reported