Fig. 2.

uhrf1 is expressed in zones of proliferation during organogenesis and in proliferating adult tissues. (A and B) In situ hybridization at 24 (A) and 34 (B) hours pf shows high levels of uhrf1 expression in rapidly proliferating cells. (C–F) At 48 h pf (C), expression has decreased in most tissues except the tectum, retina, and arches, and by 57 h (D), 4 days (E) and 5 days (F) pf, expression is evident in the liver bud and gut (arrowheads). No expression is seen in MT embryos at 4 days pf (E Inset). (G) uhrf1 message was detected in tissues from and adult male zebrafish by Q-PCR by using tbp as a reference.