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. 2007 Jan 22;104(5):1570–1575. doi: 10.1073/pnas.0610774104

Fig. 3.

Fig. 3.

Partial hepatectomy results in regeneration within 7 days. (A) Schematic of the gastrointestinal organs, viewed from the animals ventral side. The animal's left (L) and right (R) are labeled as are the dorsal (D) and ventral (V) liver lobes. The dashed line marks the site of resection of the ventral lobe. (B) Dissected gut and liver with a piece of spleen (s) attached. Ruler marks are millimeters. (C) PH in zebrafish is carried out on day 0 (Upper) by creating a small incision through the ventral body wall and the ventral lobe of the liver is resected. By day 7 (Lower), the wound has healed and a ventral lobe is evident in both sham and animals subject to PH. (D–I) H&E stained sagittal sections of fish taken at 16 h (D and E) and 4 (F and G) and 7 (H and I) days after PH or sham operation. The tip of the dorsal lobe is outlined with a dotted line and indicated with an arrow in PH samples. (Scale bars: 100 μm.)