Fig. 3.

Mint deficiency affects early T cell development before the DP stage in fetal liver transplantation assay. (A) Representative FACS profiles 6 weeks after transplantation. Each value represents the mean ± SEM of three recipient mice per group. (B) Percentages of CD45.2⁺ cells among the indicated thymocyte subsets at 6 weeks after transplantation. Each value represents the mean ± SEM of three recipient mice per group. ∗, P < 0.05 by Student's unpaired t test. (C) absolute number of CD45.2⁺ cells among thymocytes, CD3⁺ spleen T cells, and B220⁺ spleen B cells at various time points after transplantation. Each value represents the mean ± SEM of 6–10 recipient mice per group. (D) Percentages of apoptotic annexin V⁺ cells among CD45.2⁺CD3⁺ thymocytes at 8 weeks after transplantation. Each value represents the mean ± SEM of three to five mice per group.