Table 2B.

Specific lysis of CX−/CX+ target cells by NK cells stimulated with autologous or allogeneic exosomes

Target cells	Mean values of specific lysis (% ± SE)
	CX− exos	CX+ exos	Colo− exos	Colo+ exos
CX−	55 ± 4	50 ± 4	55 ± 6	42 ± 8
CX+	62 ± 3*	83 ± 3†	59 ± 4*	79 ± 6†

^*Lysis of CX−/CX+ target cells at a distinct E/T ratio of 10:1, mediated by CD94⁺ NK cells stimulated either with IL-2 plus CX− exosomes or IL-2 plus CX+ exosomes; or with IL-2 plus Colo− exosomes or IL-2 plus Colo+ exosomes, at a concentration of 10 μg/mL each. Data represent mean values of four independent experiments ± SE. Similar results were obtained if CD3/CD19-depleted NK cells were used for stimulation.

^†Means significantly different from the relevant counterpart (P < 0.005).