Table A6. .

ORs of Fetal GSTT1 Deletion and Maternal Smoking Effects in OC^[Note]

	No. of			OR
Population, Fetal GSTT1 Genotypea, and Maternal Smokingb	Cases	Controls	Total	Effectc	Value	95% CI
Iowa:
−−:
Yes	19	9	28	ORge	2.10	.92–4.70
No	30	57	87	ORg	.52	.32–.85
++/+−:
Yes	63	54	117	ORe	1.16	.76–1.76
No	180	179	359	Reference
DBS:
−−-:
Yes	20	14	34	ORge	2.80	1.37–5.61
No	21	49	70	ORg	.84	.48–1.46
++/+−:
Yes	78	128	206	ORe	1.20	.84–1.70
No	131	257	388	Reference
Iowa and DBS:
−−:
Yes	39	23	62	ORge	2.38	1.39–4.01
No	51	106	157	ORg	.67	.47–.97
++/+−:
Yes	141	182	323	ORe	1.09	.83–1.41
No	311	436	747	Reference

Note.— Data from all subjects with OC are included.

^a−− Indicates GSTT1-null genotype; ++/+− indicates not-null GSTT1 genotype (either one or two copies of the wild alleles).

^bYes or no.

^cORge is the OR of the joint GSTT1 deletion and maternal smoking versus none; ORg is OR of the GSTT1 deletion alone versus none; ORe is the OR of maternal smoking alone versus none.