Table 7. .
Transmission/Disequilibrium Tests of NAT2 G590A Marker
| No. of Subjects with Transmission |
|||||
| Sample | G | A | No. of Triads (1,1,1)a | χ2 | P |
| Case set 1b | 278 | 204 | 58 | 9.2 | .002 |
| Control set 1b | 313 | 248 | 62 | 6.2 | .013 |
| Case set 2c | 357 | 275 | 78 | 8.5 | .003 |
| Control set 2d | 450 | 434 | 111 | .2 | .630 |
| All casese | 635 | 479 | 136 | 17.6 | 3×10-5 |
| All controls | 763 | 682 | 173 | 3.7 | .056 |
a
Triad (1,1,1) represents a triad in which mother, father, and child are all heterozygous (GA).
b
Set 1 consists of the Iowa and DCS samples that are used in testing other markers.
c
Case set 2 consists of the Philippine triad samples and an additional set of Danish familial samples.
d
Control set 2 consists of the CEPH samples, affected siblings in the second set of Danish familial samples, and white control triad samples.
e
“All cases” and “All controls” represent the combined data set of set 1 and set 2.