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. 2006 Dec 7;80(1):76–90. doi: 10.1086/510518

Table 8. .

ORs by Fetal GSTT1 Genotype and Maternal Smoking Categories

Population,
GSTT1 Genotype,
and No. of
Daily Cigarettes
Case Control OR 95% CI
DBS:
 +/+ or +/−a:
  0 113 223 Reference
  1–9 34 61 1.10 .68–1.77
  10–19 54 82 1.30 .86–1.96
  20+ 8 18 .88 .37–2.08
 −/−b:
  0 18 44 Reference
  1–9 8 9 2.17 .72–6.52
  10–19 12 7 4.19 1.42–12.36
  20+ 3 3 2.44 .45–13.27
Iowa:
 +/+ or +/−c:
  0 172 180 Reference
  1–4 8 15 0.56 .23–1.35
  5–14 22 14 1.64 .82–3.32
  15+ 24 14 1.79 .90–3.58
 −/−d:
  0 30 57 Reference
  1–4 3 3 1.90 .36–10
  5–14 6 2 5.70 1.83–29.99
  15+ 9 1 17.10 2.07–141.4
a

Cochran-Armitage trend test Z=.83; P=.409.

b

Cochran-Armitage trend test Z=2.56; P=.011.

c

Cochran-Armitage trend test Z=1.85; P=.064.

d

Cochran-Armitage trend test Z=3.87; P=.0001.