Table 8. .
Population, GSTT1 Genotype, and No. of Daily Cigarettes |
Case | Control | OR | 95% CI |
DBS: | ||||
+/+ or +/−a: | ||||
0 | 113 | 223 | Reference | |
1–9 | 34 | 61 | 1.10 | .68–1.77 |
10–19 | 54 | 82 | 1.30 | .86–1.96 |
20+ | 8 | 18 | .88 | .37–2.08 |
−/−b: | ||||
0 | 18 | 44 | Reference | |
1–9 | 8 | 9 | 2.17 | .72–6.52 |
10–19 | 12 | 7 | 4.19 | 1.42–12.36 |
20+ | 3 | 3 | 2.44 | .45–13.27 |
Iowa: | ||||
+/+ or +/−c: | ||||
0 | 172 | 180 | Reference | |
1–4 | 8 | 15 | 0.56 | .23–1.35 |
5–14 | 22 | 14 | 1.64 | .82–3.32 |
15+ | 24 | 14 | 1.79 | .90–3.58 |
−/−d: | ||||
0 | 30 | 57 | Reference | |
1–4 | 3 | 3 | 1.90 | .36–10 |
5–14 | 6 | 2 | 5.70 | 1.83–29.99 |
15+ | 9 | 1 | 17.10 | 2.07–141.4 |
Cochran-Armitage trend test Z=.83; P=.409.
Cochran-Armitage trend test Z=2.56; P=.011.
Cochran-Armitage trend test Z=1.85; P=.064.
Cochran-Armitage trend test Z=3.87; P=.0001.