Table 2. .
SHFLD Loci in Family UR078 Mapped by Linkage Analysis to Chromosome 1q42.13-1q43 and 6q14.1 Regions[Note]
| Position |
NPL Multipoint LinkageGenome Scan |
||||
| SNP Marker |
Genetic (cM) |
Cytogenetic | Physical (bp) |
NPL | P |
| rs1124110 | 233.32 | 1q42.13 | 226,617,707 | 4.61 | .009373 |
| rs1933633 | 234.32 | 1q42.2 | 227,231,111 | 6.25 | .003083 |
| rs953244 | 235.28 | 1q42.2 | 228,130,318 | 7.76 | .000215 |
| rs4333837 | 235.37 | 1q42.2 | 228,331,909 | 7.84 | .000201 |
| rs967433 | 235.38 | 1q42.2 | 228,338,550 | 7.85 | .000201 |
| rs720806 | 237.54 | 1q42.2 | 228,945,997 | 8.94 | .000097 |
| rs965917 | 238.86 | 1q42.2 | 229,690,846 | 9.38 | .000086 |
| rs1294330 | 238.97 | 1q42.2 | 229,755,343 | 9.45 | .000084 |
| rs780245 | 239.42 | 1q42.2 | 230,004,265 | 9.48 | .000084 |
| rs923975 | 239.95 | 1q42.2 | 230,304,605 | 9.58 | .000084 |
| rs923976 | 239.95 | 1q42.2 | 230,304,802 | 9.58 | .000084 |
| rs955612 | 241.23 | 1q42.3 | 231,023,328 | 9.58 | .000084 |
| rs1416473 | 244.23 | 1q42.3 | 231,889,300 | 9.74 | .000084 |
| rs966302 | 245.54 | 1q42.3 | 232,585,612 | 9.79 | .000065 |
| rs1405633 | 246.04 | 1q42.3 | 232,745,539 | 9.79 | .000065 |
| rs1749569 | 246.04 | 1q42.3 | 232,745,622 | 9.79 | .000065 |
| rs966364 | 246.48 | 1q42.3 | 232,883,969 | 9.75 | .000084 |
| rs959175 | 247.01 | 1q43 | 233,078,923 | 9.71 | .000084 |
| rs1337797 | 248.33 | 1q43 | 233,625,390 | 9.44 | .000084 |
| rs950964 | 248.62 | 1q43 | 233,746,722 | 9.33 | .000086 |
| rs1074189 | 249.44 | 1q43 | 234,087,534 | 8.74 | .000109 |
| rs1361358 | 250.12 | 1q43 | 234,370,458 | 7.80 | .000215 |
| rs535043 | 251.70 | 1q43 | 235,022,077 | 5.23 | .009182 |
| rs623155 | 90.01 | 6q14.1 | 79,324,200 | 7.10 | .000897 |
| rs1415863 | 90.24 | 6q14.1 | 79,756,878 | 7.10 | .000897 |
| rs1414280 | 90.36 | 6q14.1 | 79,985,449 | 7.11 | .000897 |
| rs721265 | 90.63 | 6q14.1 | 80,549,653 | 7.10 | .001173 |
| rs719172 | 90.65 | 6q14.1 | 80,611,300 | 7.11 | .000897 |
| rs688867 | 90.78 | 6q14.1 | 80,995,947 | 7.12 | .000897 |
| rs723587 | 90.82 | 6q14.1 | 81,113,079 | 7.12 | .000897 |
| rs1902066 | 90.93 | 6q14.1 | 81,402,752 | 7.10 | .000897 |
| rs1377986 | 90.96 | 6q14.1 | 81,463,288 | 7.10 | .001173 |
| rs1584896 | 90.96 | 6q14.1 | 81,463,350 | 7.10 | .001173 |
| rs1584897 | 90.96 | 6q14.1 | 81,463,381 | 6.99 | .001266 |
| rs724993 | 91.08 | 6q14.1 | 81,799,004 | 7.02 | .001217 |
| rs962984 | 91.19 | 6q14.1 | 82,120,869 | 7.04 | .001217 |
| rs962983 | 91.19 | 6q14.1 | 82,121,184 | 7.04 | .001217 |
| rs1343232 | 91.21 | 6q14.1 | 82,187,051 | 7.04 | .001207 |
| rs719144 | 91.4 | 6q14.1 | 82,388,507 | 7.07 | .001186 |
| rs733413 | 91.6 | 6q14.1 | 82,587,633 | 7.09 | .001173 |
| rs72968 | 91.6 | 6q14.1 | 82,587,967 | 7.09 | .001173 |
| rs1931621 | 91.61 | 6q14.1 | 82,596,847 | 7.09 | .001173 |
| rs1342196 | 91.75 | 6q14.1 | 82,862,011 | 7.10 | .001173 |
| rs2226121 | 91.75 | 6q14.1 | 82,862,272 | 7.10 | .001173 |
| rs1556778 | 91.75 | 6q14.1 | 82,862,533 | 7.10 | .001173 |
| rs950611 | 91.83 | 6q14.1 | 83,023,894 | 7.10 | .001173 |
Note.— Recombination narrowed the candidate region to an interval flanked by rs1294330 and rs1361358 for chromosome 1q and to an interval flanked by rs623155 and rs1547251 for chromosome 6q.