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. 2007 Jan 18;6:1. doi: 10.1186/1476-069X-6-1

Table 1.

Linear modela

Stomach Liver Lung
gender M/F M/F M/F
casesb 1482 540 524
φmc 6.66 38.58 16.90
ca Dφ > 0d 1412 172 494
LRTlin-cone 2.09 11.21 2.26
ERR1,φfg 0.09 (-0.03, 0.22) 0.69 (0.25, 1.26) 0.16 (-0.05, 0.42)
Devh 1680.64 1258.02 1052.43
Chi-sqi 3205.08 2389.85 2500.37
dfj 2992 2992 2992
Excessk 38.13 27.17 23.20

Colon Uterus All solid

gender M/F F M/F
casesb 214 263 4379
φmc 43.91 6.12 43.86
ca Dφ > 0d 33 262 365
LRTlin-cone 0.19 0.51 5.03
ERR1, φfg 0.17 (-0.44, 1.17) 0.10 (-0.16, 0.44) 0.26 (0.03, 0.52)
Devh 719.80 638.46 2133.03
Chi-sqi 3497.50 1010.56 2769.51
dfj 2992 1513 2992
Excessk 1.51 8.88 25.01

a 0 – 20 mSv subcohort, Excess Relative Risk ERR = βDφ with β constrained by 1 + ERR 0 for all data cells. Dφ is the weighted adjusted colon dose (neutron RBE = 10), lagged by φ years, in 10 mSv units. The control model is nested by β = 0.

b deaths in the subcohort from the specified cancer

c Latency φm is chosen in the range 5 – 44 years. to minimise linear model Deviance for the given cancer site and gender. Where italicised, φm minimises Dev subject to ERR ≥ 0, equivalent to β ≥ 0

d deaths in the subcohort from the specified cancer, for which Dφ > 0 where φ = φm

e The likelihood ratio test LRTlin-con compares the fitted linear model with the control model at φm and is χ2 distributed on 1 degree of freedom

f ERR1,φ is the Excess Relative Risk at Dφ = 1 with φ = φm

g 95% Profile Likelihood Confidence Intervals are calculated with φ fixed at φm

h Deviance of the fitted model

i Pearson Chi-Square of the fitted model

j Degrees of Freedom of the fitted model

k difference between Observed (= Expected) cases and the number expected if Dφ is set to 0 in every cell after fitting the model