Skip to main content
. 2007 Jan 18;6:1. doi: 10.1186/1476-069X-6-1

Table 3.

Two-phase modela

Stomach Liver Lung
gen M/F M/F M/F
φmb 11.89 36.90 13.60
ca Dφ > 0 1311 231 506
βc 0.46 1.43 0.44
σ 119.96 290.09 37.92
τ 82.67 76.82 4.47
LRT2p-transd 15.68 16.76 0.34
LRT2p-lin 19.64 27.64 14.73
LRT2p-con 21.19 34.87 16.04
ERR0.025,φ 0.39 (0.08, 0.86) 1.10 (0.26, 2.37) 0.86 (0.14, 3.34)
ERR1,φ 0.46 (0.11, 0.94) 1.43 (0.48, 2.95) 0.88 (0.12, 3.36)
Dmaxe 0.01 0.01 0.23
ERRDmax,φ 0.54 (0.17, 1.04) 1.41 (0.50, 2.86) 3.23 (0.09, 9.39)
Dev 1661.53 1234.35 1038.66
Chi-sq 3408.01 2447.95 2770.40
df 2990 2990 2990
Rf 262.62 204.11 86.39
Excess 390.00 126.36 224.43

Colon Uterus All Solid

gen M/F F M/F
φmb 20.28 26.91 43.86
Dφ > 0 184 127 365
βc -0.74 0.47 -0.62
σ 11.32 198.10 13.10
τ 2.66 81.12 2.32
LRT2p-transd 1.32 1.83 1.14
LRT2p-lin 3.01 6.31 12.90
LRT2p-con 3.54 6.31 17.93
ERR0.025,φ 0.25 (-0.44, 1.46) 0.66 (-0.10, 2.44) 0.27 (0.05, 0.54)
ERR1,φ 0.05 (-0.53, 1.15) 0.47 (-0.32, 2.12) 0.27 (-0.04, 0.66)
Dmaxe 0.32 0.01 0.35
ERRDmax,φ 1.31 (-0.71, 1.51) 0.90 (-0.17, 2.96) 1.59 (0.03, 2.54)
Dev 716.45 632.66 2120.13
Chi-sq 3339.24 1047.11 2759.48
df 2990 1511 2990
Rf -14.36 425.41 -19.98
Excess 29.34 45.89 74.59

a 0 – 20 mSv subcohort, Excess Relative Risk ERR = βDφ + σDφ e(τDφ) MathType@MTEF@5@5@+=feaafiart1ev1aaatCvAUfKttLearuWrP9MDH5MBPbIqV92AaeXatLxBI9gBaebbnrfifHhDYfgasaacH8akY=wiFfYdH8Gipec8Eeeu0xXdbba9frFj0=OqFfea0dXdd9vqai=hGuQ8kuc9pgc9s8qqaq=dirpe0xb9q8qiLsFr0=vr0=vr0dc8meaabaqaciaacaGaaeqabaqabeGadaaakeaacqqGLbqzdaahaaWcbeqaaiabcIcaOiabgkHiTiabes8a0jabbseaenaaBaaameaacqaHgpGzaeqaaSGaeiykaKcaaaaa@358E@ with τ ≥ 0 and β,σ,τ constrained by 1 + ERR 0 for all data cells; for Dφ see Table 1. The transient model is nested by β = 0; the linear model is nested by σ = 0 or by τ = 0; the control model is nested by β = σ = 0.

b chosen in the range 5 – 44 years. to minimise two-phase model Deviance; where italicised φm minimises Dev subject to ERR0.025,φ ≥ 0, a weaker condition than β, σ ≥ 0.

c At φm, β, σ and τ are the fitted Maximum Likelihood Estimate parameter values.

d At φm, the likelihood ratio tests LRT2p-trans and LRT2p-lin compare the two-phase with the transient and linear models (χ2 on 1 df); and LRT2p-con compares the two-phase model with the control model (χ2 on 2 df)

e At φm, Dmax is the value of D giving a local maximum of ERRD,φ

f R = 1 + σ/β

Other definitions as in Table 2