Table 2.

Blood pressure, heart rate and lipid levels in different genotypes of the β2-adrenergic receptor polymorphisms.

	n	SBP mmHg	DBP mmHg	HR beats/min	n	Cholesterol mg/dl	Triglycerides mg/dl	n	HDL mg/dL	LDL mg/dL
All	429	130.5 ± 15.7	79.6 ± 9.2	76.8 ± 9.5	360	224.7 ± 39.4	171.5 ± 95.7	278	46.8 ± 14.3	146.6 ± 35.9
Codon -47
Cys/Cys	131	130 ± 1 ± 16.3	79.8 ± 9.4	77.0 ± 9.1	112	226.0 ± 40.3	168.6 ± 76.5	93	46.0 ± 14.3	148.9 ± 32.9
Cys/Arg	195	130.9 ± 15.6	79.6 ± 9.3	76.6 ± 8.9	163	222.5 ± 38.5	175.3 ± 102.5	123	47.3 ± 13.9	144.0 ± 38.6
Arg/Arg	103	130.1 ± 15.1	79.4 ± 8.7	76.9 ± 11.0	85	227.6 ± 40.1	167.9 ± 105.2	62	46.9 ± 15.5	148.3 ± 35.1
P		0.878	0.942	0.924		0.594	0.789		0.796	0.578
Codon 16
Arg/Arg	59	133.6 ± 17.2	80.9 ± 9.3	78.4 ± 9.3	53	228.2 ± 45.7	178.5 ± 114.2	39	49.7 ± 15.9	149.5 ± 34.8
Arg/Gly	197	130.0 ± 15.9	79.8 ± 9.5	76.6 ± 9.4	158	221.4 ± 38.6	164.7 ± 92.5	123	47.0 ± 14.4	143 ± 37.2
Gly/Gly	173	129.9 ± 14.9	79.0 ± 8.9	76.5 ± 9.7	149	227.2 ± 37.8	176.0 ± 91.8	116	45.7 ± 13.8	149.4 ± 34.9
P		0.268	0.389	0.371		0.345	0.496		0.305	0.348
Codon 27
Gln/Gln	109	130.7 ± 14.5	80.2 ± 9.0	77.2 ± 9.2	93	222.7 ± 42.3	175.9 ± 89.4	74	44.9 ± 14.0	145.6 ± 32.9
Gln/Glu	202	130.8 ± 15.2	79.2 ± 9.1	76.6 ± 9.2	164	225.3 ± 38.3	174.1 ± 100.9	128	47.2 ± 14.3	146.5 ± 38.2
Glu/Glu	118	130.5 ± 15.7	79.9 ± 9.5	76.8 ± 10.2	103	224.8 ± 39.4	163.3 ± 93.0	76	48.0 ± 14.8	147.8 ± 35.2
P		0.840	0.592	0.859		0.841	0.585		0.395	0.930

Comparison of blood pressure, heart rate, lipid and lipoprotein values between the different genotypes of the β2-adrenergic receptor polymorphisms in untreated patients with OSA. Total cholesterol and triglyceride levels were available for 360 patients and lipid electrophoresis for 278 patients. There were no significant differences between the genotypes.

SBP, systolic blood pressure; DBP, diastolic blood pressure; HDL, high-density lipoprotein; HR, heart rate; LDL, low-density lipoprotein.