Figure 3.

Normal pancreatic morphology and immunostaining for glucagon and insulin in HNF-3α mice. Pancreatic tissue sections showing representative islets from 3-day-old pancreata of wild-type and HNF-3α mutant mice. Sections were stained with antibodies against glucagon and insulin as described in Materials and Methods. Glucagon and insulin are detected in the characteristic cell-lineage patterns. Magnification, ×400.