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Cellular distribution of Hap46. HeLa cells were transfected with expression vector encoding the Hap46-GFP fusion protein. Cells were kept overnight at 37°C and analyzed either immediately by confocal laser-scanning microscopy (A) or after exposure to 42°C for 2 h (B). Light areas in photographs denote high fluorescence intensity. Different cells show different levels of transfection. (Bars = 10 μm.)
